Development of a malignant hyperthermia protocol
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چکیده
منابع مشابه
Development of a malignant hyperthermia protocol
Background Malignant Hyperthermia is a life-threatening condition triggered by exposure to certain general anaesthetics (halothane, sevoflurane, and desflurane) and depolarising muscle relaxants (suxamethonium). Malignant hyperthermia happens primarily due to mutation of the ryanodine receptor type 1 (RYR1), located on the sarcoplasmic reticulum in myocytes. This mutation leads to increase in c...
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''Malignant Hypothermia'' syndrome is a rare, but dangerous occurrence, the aetiology of which is not known. Up to this date 180 cases have been reported. This syndrome i's seen generally in :male children over age of two years, and especially in adolescent males. Also those people with muscular abnormalities are more susciptable to this illnes'S. Anaesthetic agent such as halothane or muscular...
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Malignant hyperthermia is a rare and fatal disorder. A 16-year-old male patient was a candidate for rhinoplasty surgery with no history of disease and previous surgery, negative family history and no history of medication use in the operating room. Maintenance of anesthesia was performed with O2, NO2 (50% -50%) and MAC isoflurane 1. Gradually, from the 80th minute after the start of the operati...
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Malignant hyperthermia (MH) is a disorder in genetically susceptible patients characterized by a hypermetabolic state triggered by agents used commonly during general anesthesia. The syndrome first was recognized in 1962 and is associated with tachycardia, muscle rigidity, increased oxygen demand, severe hyperpyrexia, metabolic acidosis, hyperkalemia, elevated serum enzyme creatinine phosphokin...
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Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle that presents as a hypermetabolic response to potent volatile anesthetic gases such as halothane, sevoflurane, desflurane, isoflurane and the depolarizing muscle relaxant succinylcholine, and rarely, in humans, to stressors such as vigorous exercise and heat. The incidence of MH reactions ranges from 1:10,000 to 1: 250...
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ژورنال
عنوان ژورنال: BMC Proceedings
سال: 2015
ISSN: 1753-6561
DOI: 10.1186/1753-6561-9-s1-a32